The most irritating color is also the most noticeable
Which color is the most irritating?
Yellow, pure bright lemon yellow is the most fatiguing color. Why? The answer comes from the physics of light and optics. More light is reflected by bright colors, resulting in excessive stimulation of the eyes. Therefore, yellow is an eye irritant. Some claim that babies cry more in yellow rooms, husbands and wives fight more in yellow kitchens, and opera singers throw more tantrums in yellow dressing rooms. However, these reports have not been scientifically proven.
In practical application, bright yellow – when used in large areas, will irritate the eyes. Therefore, do not paint the walls of an office (or any critical task environment) yellow. Note: Lighter shades of yellow can be comforting and cheerful.
Also, beware of bright yellow legal pads (but this may give you a jolt and temporarily wake your brain up) and do not use yellow as a background on your computer monitor.
On the other hand, since yellow is the most visible color of all the colors, it is the first color that the human eye notices. Use it to get attention, such as a yellow sign with black text, or as an accent. Have you noticed yellow fire engines in some cities?
Finally, yellow is a wonderful color, the most cheerful of the spectrum. And yellow is a symbol of the deity in many global religions.
~article from ColorMatters.com